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Small cell carcinoma of the urinary bladder without gross hematuria: a case report

Wanqiu Huang,Yang Luan,Lu Jin,Tao Wang,Ruibao Chen,Zheng Liu,Zhiqiang Chen,Ruzhu Lan

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 384-387 doi: 10.1007/s11684-015-0405-z

Abstract:

Small cell carcinoma of the urinary bladder (SCCB) is a rare and aggressive form of bladder cancerThe disease incidence of malignant bladder tumors in China is approximately 0.74%.report describes a patient with a single neoplasm diagnosed as SCCB that arose because of recurrence of bladdercancer after bladder tumor resection.

Keywords： carcinoma     small cell     urinary bladder neoplasms     diagnosis    

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Dynamics analysis of bladder-urethra system based on CFD

Qinghua JIN, Xiaojun ZHANG, Xiaoyang LI, Jianliu WANG,

Frontiers of Mechanical Engineering 2010, Volume 5, Issue 3,   Pages 336-340 doi: 10.1007/s11465-010-0027-8

Abstract: closure of stress urinary incontinence (SUI) patients in a clinic.system, which includes bladder, bladder neck, prostate, and urethra.The realistic recirculation process of the urinary bladder during the physiologic voiding process inconjunction with a flow simulation through the female urinary bladder and urethra is presented.The simulation results does not only improve urinary incontinence surgery for clinicians, but can also

Keywords： bladder-urethra system     stress urinary incontinence (SUI)     computational fluid dynamics (CFD)     urodynamics    

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Analysis of 100 consecutive cases of resectable pancreatic neuroendocrine neoplasms: clinicopathological

Yugang Cheng,Hanxiang Zhan,Lei Wang,Jianwei Xu,Guangyong Zhang,Zongli Zhang,Sanyuan Hu

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 444-450 doi: 10.1007/s11684-016-0471-x

Abstract:

The incidence rate of pancreatic neuroendocrine neoplasms (pNENs) has increased rapidly in recent

Keywords： pancreatic neuroendocrine neoplasms     clinicopathological characteristic     Ki-67     liver metastasis     outcomes    

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The clinicopathologic features of intraductal papillary mucinous neoplasms of the pancreas

QIN Xinyu, LIU Fenglin

Frontiers of Medicine 2007, Volume 1, Issue 2,   Pages 121-125 doi: 10.1007/s11684-007-0023-5

Abstract: Since first described in 1982, intraductal papillary mucinous neoplasm (IPMN) has been the preferred term to describe the proliferation of the pancreatic ductal epithelium. It is totally different from pancreatic carcinoma in epi demiology, histology, pathology and prognosis. According to the site of involvement, IPMNs are classified into three categories, i.e. main duct type, branch duct type, and combined type. Most branch duct IPMNs are benign, whereas the other two types are often malignant. A large branch duct IPMN and marked dilation of the main pancreatic duct indicate the presence of adenoma at least. The additional existence of large mural nodules increases the possibility of malignancy in all types. The prognosis is more favorable after complete resection of benign and non-invasive malignant IPMNs. Malignant IPMNs that become more aggressive after parenchymal invasion necessitate adequate lymph node dissection. On the other hand, asymptomatic branch duct IPMNs without mural nodules can be observed without the need for resection for a considerable period of time. Our review addresses available data, current understanding, controversy, and future directions about IPMNs.

Keywords： available     additional existence     necessitate     intraductal papillary     non-invasive    

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Can intravesical bacillus Calmette-Guérin reduce recurrence in patients with non-muscle invasive bladder

Jiangang Pan,Mo Liu,Xing Zhou

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 241-249 doi: 10.1007/s11684-014-0328-0

Abstract:

Approximately 70% of newly diagnosed bladder tumors are non-muscle invasive bladder cancer (NMIBC)NMIBC accounts for approximately 80% of total bladder cancer cases.(BCG) instillation and maintenance is considered as the standard adjuvant treatment for superficial bladder

Keywords： non-muscle invasive bladder cancer     bacillus Calmette-Guérin (BCG)     meta-analysis    

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Artificial Intelligence in Healthcare: Review and Prediction Case Studies Review

Guoguang Rong, Arnaldo Mendez, Elie Bou Assi, Bo Zhao, Mohamad Sawan

Engineering 2020, Volume 6, Issue 3,   Pages 291-301 doi: 10.1016/j.eng.2019.08.015

Abstract: provided to illustrate the prediction of epileptic seizure occurrences and the filling of a dysfunctional urinarybladder.

Keywords： learning     Deep learning Neural network     Biomedical research     Healthcare applications     Epileptic seizure     Urinarybladder filling    

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A comparative study of electroacupuncture at Zhongliao (BL33) and other acupoints for overactive bladder

Likun Yang,Yang Wang,Qian Mo,Zhishun Liu

Frontiers of Medicine 2017, Volume 11, Issue 1,   Pages 129-136 doi: 10.1007/s11684-016-0491-6

Abstract:

Electroacupuncture (EA) at Zhongliao (BL33) can improve the symptoms of overactive bladder (OAB),such as urinary frequency, urgency, and incontinence.

Keywords： overactive bladder     electroacupuncture     acupuncture points    

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randomized trials of maintenance bacillus Calmette-Guerin instillation efficacy against recurrence of T1G3 bladder

PAN Jiangang, ZHOU Xing, CHEN Zhiguang, HAN Ruifa

Frontiers of Medicine 2008, Volume 2, Issue 3,   Pages 259-263 doi: 10.1007/s11684-008-0049-3

Abstract: Calmette-Guerin (BCG) could reduce recurrence after transurethral resection of tumor 1 grade 3 (T1G3) superficial bladderresection alone or resection plus another treatment on the treatment results in patients with superficial bladderthe conclusion that adjuvant maintenance instillation BCG combined with transurethral resection of bladdertumor (TURBT) is an effective conservative treatment for preventing recurrence of T1G3 bladder cancer
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Correlation between serum miR-154-5p and urinary albumin excretion rates in patients with type 2 diabetes

Huiwen Ren, Can Wu, Ying Shao, Shuang Liu, Yang Zhou, Qiuyue Wang

Frontiers of Medicine 2020, Volume 14, Issue 5,   Pages 642-650 doi: 10.1007/s11684-019-0719-3

Abstract: This study aimed to investigate the correlation between serum miR-154-5p and urinary albumin to creatinine

Keywords： type 2 diabetes mellitus     diabetic kidney disease     miR-154-5p     urinary albumin to creatinine ratio    

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Study of recombinant human IFN-α-2b bacilli Calmette–Guerin activated killer cells and against bladder

FAN Xiaodong, HAN Ruifa

Frontiers of Medicine 2007, Volume 1, Issue 4,   Pages 377-380 doi: 10.1007/s11684-007-0073-8

Abstract: immunotherapies is the application of bacillus Calmette Guerin (BCG) to prevent recurrences of the superficial bladderBAK cells have the ability to kill bladder tumor cells, and the antitumor activity of effecter cellsWe conclude that the recombinant BCG can activate more PBMCs to anti-bladder cancer than wild-type BCG

Keywords： Urology     powerful     2b-BCG     Tianjin institute     wild-type    

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Treatment of infant postrenal acute renal failure following obstruction due to upper urinary calculi

Hui-Xia ZHOU MD, Zhi-Chun FENG MD, Hao MENG MD, Xiao-Guang ZHOU MD, Shuang LI BM, Jun WANG MM, Shi-Xi DAI BM,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 127-130 doi: 10.1007/s11684-010-0009-6

Abstract: treatments and curative effects of postrenal acute renal failure following obstruction due to upper urinaryOf the 13 infants with postrenal acute renal failure following obstruction due to upper urinary calculiinvasive, safe and effective therapy for postrenal acute renal failure following obstruction due to upper urinary

Keywords： infant     acute renal failure     postrenal     ureteroscopy    

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High frequency of alternative splicing variants of the oncogene in neuroendocrine tumors of the pancreas and breast

Frontiers of Medicine   Pages 907-923 doi: 10.1007/s11684-023-1009-7

Abstract: The characteristic genetic abnormality of neuroendocrine neoplasms (NENs), a heterogeneous group of tumors/strong>) of 45 pancreatic NENs, 19 (47.5%) of 40 pancreatic solid pseudopapillary neoplasms

Keywords： FAK6/7     SRRM4     neuroendocrine neoplasms     pancreas     breast    

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IRF4 and IRF8 expression are associated with clinical phenotype and clinico-hematological response to hydroxyurea in essential thrombocythemia

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 403-415 doi: 10.1007/s11684-021-0858-1

Abstract: The morbidity and mortality of myeloproliferative neoplasms (MPNs) are primarily caused by arterial and

Keywords： myeloproliferative neoplasms     IRF4     IRF8     hydroxyurea     essential thrombocythemia    

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Expression of PC-cell-derived growth factor in breast cancer

Haiping SONG MD, Lan SHI MD, Chunping LIU MD, Tao HUANG MD,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 426-430 doi: 10.1007/s11684-009-0085-7

Abstract: This study is mainly aimed at evaluating the expression of PC-cell-derived growth factor (PCDGF) in breast cancer and breast adenofibroma, and to compare with other commonly used clinical pathological indices, then to investigate the diagnostic and targeted therapeutic purpose of PCDGF in breast cancer tissue. In this study, we detected the expression of PCDGF, p53 and CerbB-2 in breast cancer tissue and the expression of PCDGF in breast adenofibroma tissue by immunohistochemical method, and analyzed the relationship between them. We found that PCDGF was expressed in most breast cancer tissue, but was not in breast adenofibroma tissue, and the expression of PCDGF was related with the tumor’s pathological category and the expression of estrogen receptor (ER) and progesterone receptor (PR) and p53, but there was no statistical dependability between PCDGF and cerbB-2. From this study, we predict that PCDGF may serve as a marker in the secondary diagnosis of breast cancer, and may participate in the generation and differentiation of breast cancer cells, and become an effective target of therapy for breast cancer.

Keywords： PC-cell-derived growth factor     breast neoplasms     clinical markers    

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Influence of the adjuvant therapy on the survival of patients with stage II pancreatic carcinoma

Xi-Yan WANG, Hai-Jun LI, Dong YAN, Hao WEN, Shu-Yong PENG,

Frontiers of Medicine 2010, Volume 4, Issue 4,   Pages 430-435 doi: 10.1007/s11684-010-0700-7

Abstract: This study aimed to investigate the effect of adjuvant therapy on the treatment of stage II pancreatic carcinomas. The clinical data of 139 cases of stage II pancreatic carcinoma were analyzed retrospectively. The overall 1-, 3-, and 5-year cumulative survival rates of 139 patients were 40%, 6%, and 3%, respectively, and the median survival time (MST) was 279 days. The MST was 399 days for those with adjuvant therapy, 210 days for those without adjuvant therapy, 390 days for the radical resection group, 270 days for the bypass operation and laparotomy group, and 132 days for the nonsurgical group. The adjuvant therapy could not prolong the survival time and decrease the liver metastasis rate of the patients with stage II carcinoma significantly in radical resection group (>0.05). In the bypass operation and laparotomy group and nonsurgical group, the adjuvant therapy could improve the survival of the patients significantly (<0.05); however, the survival rate was not significantly different among systemic venous chemotherapy, radiation therapy, interventional therapy, and combination therapy (>0.05); or between gemcitabine (GEM) regimen and 5-fluorouracil regimen (>0.05); or between GEM monotherapy and GEM combined with platinum/capecitabine (>0.05). The proper adjuvant therapy can be suggested according to the general condition of the patients after radical resection for stage II pancreatic carcinoma. Chemotherapy combined with radiation should be applied actively for the patients whose cancerous tissues were not radically resected. The clinical efficacy of GEM combined with platinum/capecitabine is relatively better than GEM.

Keywords： pancreatic neoplasms     neoadjuvant therapy     survival    

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Title Author Date Type Operation

Small cell carcinoma of the urinary bladder without gross hematuria: a case report

Wanqiu Huang,Yang Luan,Lu Jin,Tao Wang,Ruibao Chen,Zheng Liu,Zhiqiang Chen,Ruzhu Lan

Journal Article

Dynamics analysis of bladder-urethra system based on CFD

Qinghua JIN, Xiaojun ZHANG, Xiaoyang LI, Jianliu WANG,

Journal Article

Analysis of 100 consecutive cases of resectable pancreatic neuroendocrine neoplasms: clinicopathological

Yugang Cheng,Hanxiang Zhan,Lei Wang,Jianwei Xu,Guangyong Zhang,Zongli Zhang,Sanyuan Hu

Journal Article

The clinicopathologic features of intraductal papillary mucinous neoplasms of the pancreas

QIN Xinyu, LIU Fenglin

Journal Article

Can intravesical bacillus Calmette-Guérin reduce recurrence in patients with non-muscle invasive bladder

Jiangang Pan,Mo Liu,Xing Zhou

Journal Article

Artificial Intelligence in Healthcare: Review and Prediction Case Studies

Guoguang Rong, Arnaldo Mendez, Elie Bou Assi, Bo Zhao, Mohamad Sawan

Journal Article

A comparative study of electroacupuncture at Zhongliao (BL33) and other acupoints for overactive bladder

Likun Yang,Yang Wang,Qian Mo,Zhishun Liu

Journal Article

randomized trials of maintenance bacillus Calmette-Guerin instillation efficacy against recurrence of T1G3 bladder

PAN Jiangang, ZHOU Xing, CHEN Zhiguang, HAN Ruifa

Journal Article

Correlation between serum miR-154-5p and urinary albumin excretion rates in patients with type 2 diabetes

Huiwen Ren, Can Wu, Ying Shao, Shuang Liu, Yang Zhou, Qiuyue Wang

Journal Article

Study of recombinant human IFN-α-2b bacilli Calmette–Guerin activated killer cells and against bladder

FAN Xiaodong, HAN Ruifa

Journal Article

Treatment of infant postrenal acute renal failure following obstruction due to upper urinary calculi

Hui-Xia ZHOU MD, Zhi-Chun FENG MD, Hao MENG MD, Xiao-Guang ZHOU MD, Shuang LI BM, Jun WANG MM, Shi-Xi DAI BM,

Journal Article

High frequency of alternative splicing variants of the oncogene in neuroendocrine tumors of the pancreas and breast

Journal Article

IRF4 and IRF8 expression are associated with clinical phenotype and clinico-hematological response to hydroxyurea in essential thrombocythemia

Journal Article

Expression of PC-cell-derived growth factor in breast cancer

Haiping SONG MD, Lan SHI MD, Chunping LIU MD, Tao HUANG MD,

Journal Article

Influence of the adjuvant therapy on the survival of patients with stage II pancreatic carcinoma

Xi-Yan WANG, Hai-Jun LI, Dong YAN, Hao WEN, Shu-Yong PENG,

Journal Article